The RYK antibody from Wuhan Fine Biotech Co., Ltd. is a Rabbit Polyclonal antibody to receptor like tyrosine kinase, and RYK. This antibody recognizes Homo Sapiens, Human, Mouse, and Rat antigen. The RYK antibody has been validated for the following applications: EIA, Immunoassay, ELISA, Immunofluorescence, Immunohistochemistry, and Western Blot.
Description
May be a coreceptor along with FZD8 of Wnt proteins, such as WNT1, WNT3, WNT3A and WNT5A. Involved in neuron differentiation, axon guidance, corpus callosum establishment and neurite outgrowth. In response to WNT3 stimulation, receptor C-terminal cleavage occurs in its transmembrane region and allows the C-terminal intracellular product to translocate from the cytoplasm to the nucleus where it plays a crucial role in neuronal development